腸脳軸
Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study
Authors: Gunilla Önning,Caroline Montelius, Magnus Hillman, and Niklas Larsson
Publication: Nutrients (2023) 15 (15), 3466
Intake of Lactiplantibacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress: A randomized, double blind, placebo-controlled study
Authors: Gunilla Önning, Magnus Hillman, Maria Hedin, Caroline Montelius, Joakim Eriksson, Siv Ahrné and Peter Jönsson
Publication: Physiology & behavior, 225, 113083.
Oral Administration of S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HEAL9 Improves the Mild-To-Moderate Symptoms of Depression: A Randomized, Double-Blind, Placebo-Controlled Study
Authors: Saccarello A, Montarsolo P, Massardo I, Picciotto R, Pedemonte A, Castagnaro R, Brasesco PC, Guida V, Picco P, Fioravanti P, Montisci R, Schiavetti I, Vanelli A.
Publication: The primary care companion for CNS disorders, 22(4), 19m02578
消化器系の健康
Review: Antibiotics and Probiotics for Irritable Bowel Syndrome
Authors: Goodoory, V.C., Ford, A.C.,
Publication: Drugs 83(8):687-699.
Intake of Lactobacillus plantarum reduces certain gastrointestinal symptoms during treatment with antibiotics.
Authors: Lönnermark, E., Friman, V., Lappas, G., Sandberg, T., Berggren, A., Alderberth, I.
Publication: Journal of Clinical Gastroenterology 44: 106-112
Probiotic therapy to men with incipient arteriosclerosis initiates increased bacterial diversity in colon: A randomized controlled trial
Authors: Karlsson, C., Ahrné, S., Molin, G., Berggren, A., Palmquist, I., Fredrikson, G.N., Jeppsson, B.
Publication: Atherosclerosis, Volume 208, Issue 1.
Lactobacillus plantarum 299v Reduces the Incidence of Clostridium difficile Infection in Nephrology and Transplantation Ward-Results of One Year Extended Study
Authors: Dudzicz, S., Kujawa-Szewieczek, A., Kwiecień, K., Więcek, A., Adamczak, M.
Publication: Nutrients, 10(11), 1574.
Treatment of IBS with Lactobacillus plantarum 299v: Therapeutic success increases with length of treatment – real-life data of a non-interventional study in Germany
Authors: Krammer H, Storr M, Madisch A, Riffel J
Publication: Z Gastroenterol 2021; 59(02): 125-134
Please note that the publication is only available in German, but with an abstract in English
Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.
Authors: Ducrotté P, Sawant P, Jayanthi V.
Publication: World J Gastroenterol. 2012;18(30):4012-8.
A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome
Authors: Niedzielin K, Kordecki H, Birkenfeld B
Publication: Eur J Gastroenterol Hepatol. 2001;13(10):1143-7.
Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome
Authors: Nobaek S, Johansson M L, Molin G, Ahrné S, Jeppsson B
Publication: Am J Gastroenterol. 2000;95(5):1231-8.
Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats
Authors: Johansson M L, Nobaek S, Berggren A, Nyman M, Björck I, Ahrné S, Jeppsson B, Molin G
Publication: Int J Food Microbiol. 1998;42(1-2):29-38.
免疫の健康
Probiotics for preventing acute upper respiratory tract infections.
Authors: Zhao, Y., Dong, B.R., Hao, Q.
Publication: Cochrane Database of Systematic Reviews 2022, Issue 8. Art. No.: CD006895.
Effects of Lactobacillus plantarum and Lactobacillus paracasei on the Peripheral Immune Response in Children with Celiac Disease Autoimmunity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Authors: Håkansson, Å., Andrén Aronsson, C., Brundin, C., Oscarsson, E., Molin, G., Agardh, D.
Publication: Nutrients 11: 1925
Probiotic use in the prophylaxis of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: a retrospective cohort study.
Authors: Batu, E.D., Akca, U.K., Basaran, O., Bilginer, Y., Özen, S.
Publication: Rheumatology International, 42, 1207- 1211
Differential effect on cell-mediated immunity in human volunteers after intake of different lactobacilli
Authors: Rask C, Adlerberth I, Berggren A, Ahrén I L, Wold A E
Publication: Clin Exp Immunol. 2013;172(2):321-32.
Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections
Authors: Berggren A, Lazou Ahrén I, Larsson N, Önning G
Publication: Eur J Nutr. 2011;50(3):203-10.
Randomized, double blind and placebo controlled study using a combination of two probiotic lactobacilli to alleviate symptoms and frequency of common cold
Authors: Busch R, Gruenwald J, Dudek S
Publication: Food Nutr Sci. 2013;4:13-20.
Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study.
Authors: Lazou Ahrén I, Berggren A, Teixeira C, Martinsson Niskanen T, Larsson N.
Publication: Eur J Nutr. 2020 Feb;59(1):409-417.
鉄の吸収
Feasibility Study of Lactobacillus Plantarum 299v Probiotic Supplementation in an Urban Academic Facility among Diverse Pregnant Individuals.
Authors: OjiNjideka Hemphill, N., Pezley, L., Steffen, A., Elam, G., Kominiarek, M. A., Odoms-Young, A., Kessee, N., Hamm, A., Tussing-Humphreys, L., Koenig, M. D.
Publication: Nutrients, 15(4), 875
The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial
Authors: Axling U, Önning G, Martinsson Niskanen T, Larsson N, Hansson S R, Hulthén L
Publication: Acta Obstet Gynecol Scand. 2021 Apr 21. (epub ahead of print)
A lactic acid-fermented oat gruel increases non-haem iron absorption from a phytate-rich meal in healthy women of childbearing age
Authors: Bering S, Suchdev S, Sjoltov L, Berggren A, Tetens I, Bukhave K
Publication: Br J Nutr. 2006;96(1):80-5.
Probiotic strain Lactobacillus plantarum 299v increases iron absorption from an iron-supplemented fruit drink: a double-isotope cross-over single-blind study in women of reproductive age
Authors: Hoppe M, Önning G, Berggren A, Hulthén L
Publication: Br J Nutr. 2015; 114(8): 1195–1202.
Freeze-dried Lactobacillus plantarum 299v increases iron absorption in young females—Double isotope sequential single-blind studies in menstruating women
Authors: Hoppe M, Önning G, Hulthén L
Publication: PLoS One. 2017; 12(12): e0189141.
The Effect of Lactobacillus plantarum 299v on Iron Status and Physical Performance in Female Iron-Deficient Athletes: A Randomized Controlled Trial.
Authors: Axling U, Önning G, Combs MA, Bogale A, Högström M, Svensson M.
Publication: Nutrients. 2020;12(5):1279.
骨の健康
Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice.
Authors: Sophocleous, A., Azfer, A., Huesa, C., Stylianou, E., & Ralston, S. H.
Publication: Calcified tissue international, 112(1), 66–73.
A probiotic mix partially protects against castration-induced bone loss in male mice
Authors: Lina Lawenius, Hannah Colldén, Karin L Gustafsson, Jianyao Wu, Louise Grahnemo, Liesbeth Vandenput, Claes Ohlsson, Klara Sjögren
Publication: J Endocrinol 2022;254(2):91-101.
Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in mice
Authors: Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
Publication: Am J Physiol Endocrinol Metab. 2021;320(3):E591-E597
A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
Authors: Lavasani S, Dzhambazov B, Nouri M, Fåk F, Buske S, Molin G, Thorlacius H, Alenfall J, Jeppsson B, Weström B
Publication: PLoS One. 2010;5(2):e9009.
Probiotics protect mice from ovariectomy-induced cortical bone loss
Authors: Ohlsson C, Engdahl C, Fåk F, Andersson A, Windahl S H, Farman H H, Movérare-Skrtic S, Islander U, Sjögren K
Publication: PLoS One. 2014;9(3):e92368.
Probiotic treatment using a mix of three Lactobacillus strains for lumbar spine bone loss in postmenopausal women: a randomised, double-blind, placebo-controlled, multicentre trial
Authors: Jansson P-A, Curiac D, Lazou Ahrén I, Hansson F, Martinsson Niskanen T, Sjögren K, Ohlsson C
Publication: The Lancet Rheumatology 2019;1(3):e154-e162.
口腔の健康
Effect of Probiotic Streptococcus salivarius K12 and M18 Lozenges on the Cariogram Parameters of Patients With High Caries Risk: A Randomised Control Trial
Authors: Saravanan Poorni, M S Nivedhitha, Manali Srinivasan, Arthi Balasubramaniam
Publication: Cureus,14(3), e23282
Does Streptococcus Salivarius Strain M18 Assumption Make Black Stains Disappear in Children?
Authors: Elena Bardellini, Francesca Amadori, Emanuela Gobbi, Anna Ferri, Giulio Conti, Alessandra Majorana
Publication: Oral health & preventive dentistry, 18(1), 161–164.
Use of Streptococcus salivarius K12 to reduce the incidence of pharyngo-tonsillitis and acute otitis media in children: a retrospective analysis in not-recurrent pediatric subjects
Authors: Francesco Di Pierro, Paolo Risso, Elena Poggi, Anna Timitilli, Sara Bolloli, Maurizio Bruno, Egidio Caneva, Riccardo Campus, Alessandro Giannattasio
Publication: Minerva pediatrica, 70(3), 240–245.
Clinical evaluation of the oral probiotic Streptococcus salivarius K12 in the prevention of recurrent pharyngitis and/or tonsillitis caused by Streptococcus pyogenes in adults
Authors: Francesco Di Pierro, Teresa Adami, Giuliana Rapacioli, Nadia Giardini, Christian Streitberger
Publication: Expert opinion on biological therapy, 13(3), 339–343.
代謝の健康
Cardiometabolic benefits of Lacticaseibacillus paracasei 8700:2: A randomized double-blind placebo-controlled trial
Authors: Jialu Yang, Jingyi Huang, Zhihao Huang, Yingxi Xu, Wenkang Li, Shanshan Zhu, Yawen Zhao, Bingqi Ye, Ludi Liu, Jiangyuan Zhu, Min Xia, Yan Liu
Publication: Clinical nutrition, 42(9), 1637–1646.
Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation.
Authors: Hofeld, B. C., Puppala, V. K., Tyagi, S., Ahn, K. W., Anger, A., Jia, S., Salzman, N. H., Hessner, M. J., & Widlansky, M. E.
Publication: Scientific reports, 11(1), 3972.
Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers.
Authors: Naruszewicz, M., Johansson, M.L., Zapolska-Downar, D., Bukowska, H.
Publication: American Journal of Clinical Nutrition 76: 1249-1255
Lactobacillus plantarum 299v supplementation improves vascular endothelial function and reduces Inflammatory biomarkers in men with stable coronary artery disease.
Authors: Malik, M., Suboc, T. M., Tyagi, S., Salzman, N., Wang, J., Ying, R., Tanner, M. J., Kakarla, M., Baker, J. E., Widlansky, M. E.
Publication: Circulation Research. 123(9):1091-1102.