On Oct 6-8 we will be attending both CPHI in Milan and CRN Annual Signature Event in Carlsbad, California. Hope to meet you there!
Meet us at ISAPP 2026 in Tokyo Oct 6-8 and don't miss our poster session.
Probi’s newest offering, a novel postbiotic solution is designed to deliver targeted gut and immune support with superior stability across modern food and beverage applications and complex supplement formulations.
Today’s consumers are actively seeking science-backed solutions that support everyday health, especially for gut health and immunity.
Brands and manufacturers face real formulation challenges with live probiotics:
- Stability across the shelf life
- Sensitivity to heat and processing
- Cold chain requirements
Rham271h solves these challenges without compromising functionality.
Postbiotics are a preparation of inanimate microorganisms and/or they components that confers a health benefit on the host.
That means they consist of non-living microbial cells or cell fragments that are:
- Heat treated
- Sometimes accompanied by their metabolites
- No longer capable of colonizing
- Biologically active in ways that support health
Targeted and consistent functionality
High stability in a wide range of applications
Significant flexibility in formulation
Built on decades of microbiome expertise, Rham271h is the postbiotic version of Lacticaseibacillus rhamnosus 271 (DSM 6594) developed to unlock new opportunities in functional nutrition.
No cold chain or viability considerations
Stable throughout shelf life and processing
Compatible with diverse ingredients and formats
Enables applications where probiotics present challenges
Supports everyday gut and immune health
Meets growing demand for health-focused food and beverages
Neutral taste, texture, and appearance
Suitable for daily consumption
Clean-label friendly
Rham271h is derived from the well-characterized probiotic strain Lacticaseibacillus rhamnosus 271 (DMS 6594). The heat-killed strain retains biological activity while offering enhanced stability to pH, heat, and shelf conditions, with documented effects on microbiota composition and immune function.
The probiotic version (Rham271™) has demonstrated the ability to support microbial balance and immune-related outcomes
In vitro studies show that Rham271h retains key bioactive properties, including the ability to modulate immune markers in its postbiotic form
Rham271h postbiotic interacts with the body via well-defined biological mechanisms:
Helps maintain immunity and gut barrier integrity/function
Modulates immune responses, supporting balance and resilience
Rham271h enables stable, scalable solutions across a wide range of functional applications:
A vibrant, ready-to-drink juice delivering gut support in a refreshing, everyday format.
Convenient, ready-to-mix powders that transform water into a functional beverage — anytime, anywhere.
A delicious, consumer-friendly format combining functionality with convenience — no pills required.
Demand for gut and immune health continues to rise globally:
Postbiotics are emerging as a fast-growing category, offering scientific credibility combined with formulation flexibility for next-generation products.
To learn more, read our article "Expanding microbiome innovation with postbiotics" in Nutraceutical Business Review.
At Probi, partnership means more than supplying an ingredient. Backed by decades of microbiome expertise and clinically documented strain heritage, Probi delivers solutions you can trust. With reliable quality and supply, and hands-on support from concept to commercialization, you gain a partner focused on turning science into successful products.
Unlock new possibilities in functional food and beverage innovation with a postbiotic designed for performance.
To access brochures, specifications, clinical studies, insights, and more, kindly fill in your contact details below. Our terms of use for downloading materials can be found here.
Because local laws and regulations related to the distribution, marketing and sale of ingredients and finished products vary, Probi disclaims any regulatory compliance, warranties, product guidance or instruction of any kind. This brochure is provided for business-to-business communication and educational purposes only without warranties of any kind. Users should seek legal and/or regulatory advice prior to the market introduction of any Probi strain and before use of any claims to ensure compliance and thereafter on an ongoing basis when required.
just a testing value, ignore this string please