Bone Health


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Strong bones for an active life

A healthy and active life depends on strong bones. Bone tissue is continuously built up and broken down (resorbed). In most people younger than 30, the remodeling of bone tissue follows a predictable, balanced pattern. However, after the age of 30, bone breakdown (resorption) outstrips the formation of new bone.

For women, bone resorption (and consequently bone loss), accelerates as estrogen levels decline during menopause. This acceleration increases the risk of osteoporosis and resulting fractures.

More than 20 million European women and men over the age of 50 are diagnosed with osteoporosis1 each year. The condition causes more than 8.9 million fractures annually—a rate of one fracture every three seconds.1 One in three women and one in five men over the age of 50 will experience this type of fracture.

Factors that help build strong bones include adequate dietary calcium and vitamin D, weight-bearing exercise, limited consumption of alcohol, and not smoking. Calcium and vitamin D deficiency is uncommon in the developed world and excess intake of these nutrients has not been shown to benefit bone formation. Increased physical activity benefits many aspects of life, including bone health; nevertheless, compliance with exercise regimes remains low.

Increased risk for women and seniors

Retaining bone strength is important for both men and women. However, beginning in their 30s, women are at greater risk for bone loss. Probiotics can help maintain bone mineral content in postmenopausal women and seniors, enabling them to stay active.

1. The International Osteoporosis Foundation

How can probiotics help?

As part of the normal remodeling cycle of the skeleton, the body continuously resorbs old bone and forms new. Certain probiotic bacteria have been shown to impact various stages of the bone remodeling cycle, especially bone resorption. Probiotics may positively affect bone measures, which are all involved in the normal progression of remodelling.

How can Probi® help?

Probi® Osteo is a probiotic bone health concept, based on the combination of the proprietary strains Lactiplantibacillus plantarum HEAL9 (HEAL9™), Lactiplantibacillus plantarum HEAL19 and Lacticaseibacillus paracasei 8700:2.

Probi® Osteo has been studied in both preclinical and clinical settings. Preclinical studies suggest that probiotics may support normal inflammatory responses, which when elevated have been coupled to increased bone resorption. A recent randomized, double-blind, placebo-controlled clinical study2 monitored the impact of Probi Osteo on the bone density of 249 healthy, early postmenopausal women over a 12-month period. The results of the study showed that intake of Probi Osteo may reduce bone loss and support strong and healthy bones. Learn more

2. Jansson et al. 2019, The Lancet Rheumatology, doi: 10.1016/s26659913(19)30068-2

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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