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More than 70% of immune system originates in the gastrointestinal tract, making gut microbiota a key component of an efficient immune system. Maintaining the balance between good and bad bacteria is as important for immune health as it is for digestive health.
Various functions of the immune system lead either to increased or decreased activity by specific types of immune cells, whose job it is to maintain balance between pro-inflammatory and anti-inflammatory states. For example, pro-inflammatory activity is needed to identify and fight infection as quickly as possible, while anti-inflammatory activity is needed to control the body’s inflammatory response and to prevent an excessive immune reaction. This immunological balance is associated with a healthy state.
According to the World Health Organization, the high incidence of respiratory infections among the general population carries a significant socio-economic cost, despite the fact the majority of infections are confined to the upper respiratory tract, sometimes leading to coughs and colds. It is estimated that most children have 6–8 common cold episodes per year, while adults have 2–4.
Recent consumer data from Europe and Africa indicates that up to 90% of the population is interested in products that support immunity.1 Developing new ways to support the immune system may be especially important for families with young children, many of whom experience multiple upper respiratory tract infections (URTI) each year, and risk passing them on to other family members. Additional target groups include athletes, who frequently push the limits of endurance and consequently their immune systems; and the elderly, whose immune systems gradually grow less active over time as part of the normal aging process.
Improved immune health is important for everyone. A strong, “ready to go” immune system may decrease the risk of acquiring infections, while an efficient immune system may reduce the severity of symptoms and support a faster recovery for those who do become infected. Improved immune health leads to better general health, supports a sense of wellbeing, and decreases the risk of developing other conditions.
1. Consumer survey by independent company, 2020.
Because the majority of our immune cells are localized in the gut, the composition of the gut microbiota plays an important role in the development of the immune system in early life, and in the maintenance of this system throughout adulthood and aging. A well-balanced gut microbiota is the foundation of a strong and healthy life.
Several studies suggest that probiotic bacteria may impact immune health by interacting directly with intestinal cells, by secreting compounds that affect the immune system, and by altering the composition of the gut microbiota. Multiple clinical studies have shown that specific probiotics can strengthen the immune system, potentially boosting immune response time, while reducing the low-grade inflammation that may contribute to serious conditions.
Probi probiotics may support a well-balanced and diverse intestinal environment - the building blocks of a healthy, functioning immune system. Probi offers several strains, including many backed by extensive clinical studies, and many that have been specially developed to support immune health.
Probi Defendum® is a clinically studied probiotic concept consisting of a combination of the strains Lactiplantibacillus plantarum HEAL9 (HEAL9™) and Lacticaseibacillus paracasei 8700:2. The efficacy and safety of Probi Defendum have been investigated in multiple state-of-the-art clinical studies focused on respiratory health, with more than 1700 healthy subjects in total, including both adults and children. Learn more
Probi Paracasei 13434 has been studied preclinically and clinically, in trials focused on the normalization and strengthening of immune responses, as well as in studies related to general health.
Probi Rhamnosus 6594 has been preclinically and clinically studied, in trials focused on general health and immune support, including in children younger than one year.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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